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How to increase your odds of surviving COVID-19 and other respiratory viruses Part II

How to increase your odds of surviving COVID-19 and other respiratory viruses Part II


N-acetyl-cysteine (NAC) is an antioxidant that also has some anti-viral properties.  NAC is probably one of the more important supplements to take. NAC helps the body make glutathione and increases natural glutathione production.  NAC can also inhibit inflammatory cytokines such as IL-6, IL-8, and TNF-α. NAC also has benefits for those who have COPD. A minimal effective dose is 600 mg twice daily, but much higher doses may be required in times of illness; the normal oral dose can be doubled or even tripled.  The maximum tolerated oral dose of NAC seems to be around 4 g (in divided doses), but this may vary between individuals. 

Liposomal glutathione or S-acetyl-glutathione can be used together with or instead of NAC. Liposomal glutathione does not taste good, but it is powerful, so start with a few drops or 1/4 tsp. Glutathione may have anti-inflammatory effects in the lungs, and may help balance the immune system. Respiratory virus infection is associated with pulmonary damage due to decreased glutathione levels in the lungs and increased oxidative stress.  For patients with a compromised respiratory function, we recommend nebulizing glutathione. Nebulizable glutathione is by prescription only. Oral supplementation with N-acetyl cysteine and glycine can naturally increase glutathione production. B vitamins including B6 are also needed in glutathione production, so taking an Active B-complex may be of benefit.

Terry Pfau DO, HMD

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