Exosomes

Innate Regenerative Capacity

What are Exosomes?

Exosomes are derived from flotsam in the body that was once considered to be useless junk. 

Work in this area started about fifty years ago, when scientists first discovered what seemed to be tiny little pieces of cell membranes floating in the body.  They thought the membranes were cellular garbage.

But now a growing number of researchers believe this “garbage” may revolutionize medicine and lead to anti-aging treatments that will be breathtaking in their effects.

Exosomes are extremely small, fluid-filled sacs containing various proteins that cells use to communicate with each other: signaling proteins.  And just as you wouldn’t drop a letter in a mailbox without first putting it in an envelope, cells put their messenger chemicals into exosomes – containers that protect their contents with a special type of membrane.

The most exciting exosomes for anti-aging researchers are the ones produced by stem cells.  It appears that inside these little message packets are the secret codes that stimulate the body to repair itself in stunning ways

According to Douglas Spiel, the medical director of Kimera Labs and who practices medicine in New Jersey, exosomes have such great potential for fighting aging that “I believe in our very near future, we’re going to be able to have an anti-aging longevity serum.   We can give you younger patients’ exosomes.” 

The exosomes Dr Spiel is talking about are derived from stem cells taken from amniotic fluid of newborns.

Clinical Experience With Exosomes

Among his patients, says Dr. Spiel, treatment with exosomes has proven to be extremely effective – “ Parkinson’s patients who come in on canes who within three to four months can run and catch footballs.  Alzheimer’s patients who have shown cognitive changes in as little as two weeks.  I have seen motor changes in spinal cord injuries in two days.  We’re seeing really remarkable findings and we’re seeing then in autoimmune disease in my practice. 

Studies have also begun to supply evidence that exosome treatment may turn out to be a medical game changer because of its potential to:

• Reverse cellular aging in the body’s stem cells: Lab tests at Johns Hopkins show that exosomes may be able to revive older senescent (inactive) stem cells and restore their regenerative capacity for repairing the body.
• Slow the entire body’s aging process: A study at the Albert Einstein College of Mediine found that exosomes in the brain’s hypothalamus (the brain’s aging-control center) “led to the slowing of aging” in animal tests.
• Reduced fatal heart problems during diabetes. Tests at the University of Alabama are exploring the possibility that exosomes spur immune cell cleanup of dead coronary cells and lower the risk of heart failure after heart attacks in people with diabetes.